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10 American Startups Using Generative AI to Level-Up the Gaming Industry

by | Apr 6, 2025 | AI/Artificial Intelligence, Gaming industry, PE/VC/Business angels

From LA to Austin, meet the AI-powered game-changers reshaping how we play.

Generative AI is rewriting the playbook in game developmentโ€”from automated world-building to dynamic storytelling and smarter NPCs. Across the U.S., startups are racing to unlock new possibilities, fueled by venture capital and state-level ecosystem momentum. These ten American-born companies are leading the charge.

1. Jabali โ€“ San Francisco, CA & Raleigh, NC
Seed Raised: $5M
Jabaliโ€™s generative AI engine turns simple prompts into playable gamesโ€”no coding needed. Founded by ex-Amazon, Meta, and Riot Games talent, Jabali bridges two rising tech scenes: the Bay Area and North Carolinaโ€™s Research Triangle. It raised $5M in March 2024 and is already a standout in both ecosystems.

2. Series AI โ€“ Los Angeles, California
Series A: $28M
Based in LAโ€™s media-tech hotbed, Series AI is building the Rho Engine to automate game developmentโ€”from level design to dialogue. With a $28M Series A backed by Netflix and Dell Technologies Capital, Series AI is making big waves in SoCalโ€™s dynamic gaming and entertainment crossover scene.

3. Titan AI โ€“ Berkeley, California
Pre-Seed: $500K+
Titan AI is tackling mobile game development using generative AI to generate 2D/3D assets at scale. Their first title, Aztec Spirit Run, is a nod to culturally rich narratives. Backed by Berkeley SkyDeck, this East Bay upstart is gaining momentum in Californiaโ€™s university-driven startup surge.

4. Modl.ai โ€“ San Francisco, California
Raised: $8.4M+ (Globally)
Originally from Copenhagen, Modl.ai now has a firm foothold in San Francisco. Their AI simulates gameplay to spot bugs and optimize level designโ€”essentially, QA testing on autopilot. As the Bay Area reclaims its gaming edge, Modl.ai is one of its most promising new tools.

5. AvatarOS โ€“ Los Angeles, California
Seed: $8M
AvatarOS crafts AI-generated avatars that move, speak, and evolve with players. Based in LA and backed by Andreessen Horowitzโ€™s Games Fund and M13, the $8M seed-funded startup is blurring lines between character creation and virtual influencers.

6. Niantic Spatial โ€“ San Francisco, California
Spinoff Valuation: $4B
A spinout from Niantic Labs (Pokรฉmon GO), Niantic Spatial is focused on building a real-time 3D map of the world using AI and player-generated data. Though still early, its massive $4B valuation signals confidence in the Bay Areaโ€™s vision of a geo-AI-powered gaming future.

7. Inworld AI โ€“ Mountain View, California
Total Raised: $50M+
Located in the heart of Silicon Valley, Inworld AI creates AI-powered characters that think, talk, and remember. With over $50M in funding from Kleiner Perkins and Intel Capital, Inworld is leading the shift toward immersive, dynamic NPCsโ€”perfect for story-rich games.

8. Hidden Door โ€“ New York, New York
Series A: $7M
Out of NYCโ€™s growing creative-tech scene, Hidden Door transforms existing stories into interactive multiplayer experiences using generative AI. With $7M raised and partnerships in publishing, theyโ€™re showing how AI can breathe new life into narrative gaming.

9. Speech Graphics โ€“ Boulder, Colorado
Raised: $13M+
Speech Graphics adds realistic facial animations to AI dialogue in real time. From their base in Boulder, theyโ€™re helping AAA studios and indie teams alike improve emotional realism in games. Their $13M+ funding has placed them at the center of Coloradoโ€™s budding gaming-tech ecosystem.

10. Latitude (AI Dungeon) โ€“ Provo, Utah
Total Raised: $5.4M
Best known for AI Dungeon, Latitude was early to generative gaming. Based in Provo, Utah, theyโ€™re now expanding into a full studio for AI-native games. With $5.4M in funding, Latitude is fueling Utahโ€™s rise as a serious player in the creative AI space.

Market Forecast: Gamingโ€™s Next Cheat Code
The global generative AI in gaming market hit $922M in 2022 and is forecasted to surge to $7.1B by 2032โ€”a 23.3% CAGR. In the U.S., generative AI broadly is projected to reach $4.06B by 2023, growing at a 36.3% CAGR through 2030.

With game development costs soaring and content demands growing, generative AI is the power-up the industry neededโ€”and these startups are pressing โ€œStartโ€ on the next generation of interactive experiences.

Damalion supports startups of various sectors to raise funds (from pre-seed to series A, B, C). To win your fundraise, please contact your Damalion expert now.

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